Journal of Dental Implants

REVIEW ARTICLE
Year
: 2022  |  Volume : 12  |  Issue : 1  |  Page : 10--16

Systemic medications and implant success: Is there a link? part one: The effects of antihypertensives, oral hypoglycaemic agents and insulin on the outcome of implant therapy


Prema Sukumaran1, Dionetta Delitta Dionysius2, Wei Cheong Ngeow3, Chuey Chuan Tan3, Mohd Zamri Hussin1 
1 Department of Restorative Dentistry, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia
2 Department of Oral and Maxillofacial Surgery, Hospital Sultanah Nora Ismail, Johor, Malaysia
3 Department of Oral and Maxillofacial Clinical Sciences, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia

Correspondence Address:
Dr. Prema Sukumaran
Department of Restorative Dentistry, Faculty of Dentistry, University of Malaya, Kuala Lumpur 50603
Malaysia

Dental implants require healthy bone for successful osseointegration. However, bone health can become compromised by ageing and/or the presence of underlying medical conditions. The severity and complications associated with these medical conditions usually indicate that they require medication for successful management. Some of these medications may undoubtedly exert effects on bone through direct or indirect mechanisms and therefore, may also affect osseointegration. These include antihypertensives, oral hypoglycaemic agents (OHAs)/insulin, hormones (corticosteroid, thyroxin and tamoxifen) and anti-resorptive agents including bisphosphonates and anti-angiogenic agents. Part One of this paper reviews the current knowledge regarding the effects of antihypertensives, OHAs and insulin on the outcome of implant therapy.


How to cite this article:
Sukumaran P, Dionysius DD, Ngeow WC, Tan CC, Hussin MZ. Systemic medications and implant success: Is there a link? part one: The effects of antihypertensives, oral hypoglycaemic agents and insulin on the outcome of implant therapy.J Dent Implant 2022;12:10-16


How to cite this URL:
Sukumaran P, Dionysius DD, Ngeow WC, Tan CC, Hussin MZ. Systemic medications and implant success: Is there a link? part one: The effects of antihypertensives, oral hypoglycaemic agents and insulin on the outcome of implant therapy. J Dent Implant [serial online] 2022 [cited 2023 Mar 21 ];12:10-16
Available from: https://www.jdionline.org/article.asp?issn=0974-6781;year=2022;volume=12;issue=1;spage=10;epage=16;aulast=Sukumaran;type=0